Now showing items 1-10 of 161
Gray matter hypertrophy and thickening with obstructive sleep apnea in middle-aged and older adults
Gray matter increases with obstructive sleep apnea
(American Thoracic Society, 2017-06-01)
Rationale: Obstructive sleep apnea causes intermittent hypoxemia, hemodynamic fluctuations, and sleep fragmentation, all of which could damage cerebral gray matter that can be indirectly assessed with neuroimaging. Objectives: ...
Obstructive sleep apnea and the risk of cognitive decline in older adults
(American Thoracic Society, 2019-01-15)
Obstructive sleep apnea causes intermittent hypoxia and sleep fragmentation and affects at least 20% of individuals after the age of 65. There is accumulating evidence that obstructive sleep apnea may impact brain structure ...
Pathways of association between childhood irritability and adolescent suicidality
Objective Childhood irritability predicts suicidal ideation/attempt (suicidality), but it is unclear whether irritability is an independent and direct risk factor for suicidality or a marker of intermediate mental health ...
Pathways to recovery among homeless people with mental illness: Is impulsiveness getting in the way?
Objective: This study investigates the association between impulsiveness and six dimensions of recovery among homeless people with mental illness. Method: The sample was composed of 418 participants of a randomized ...
Interleukin-8 predicts fatigue at 12 months post-injury in children with traumatic brain injury
Interleukin‐8 predict fatigue in child TBI
(Mary Ann Liebert, 2019-12-27)
Despite many children experiencing fatigue after childhood brain injury, little is known about the predictors of this complaint. To date, traditional indices of traumatic brain injury (TBI) severity have not reliably ...
A phase 2 study of trametinib for patients with pediatric glioma or plexiform neurofibroma with refractory tumor and activation of the MAPK/ERK pathway
Background Pediatric low-grade gliomas (PLGG) are the most frequent brain tumors in children. Up to 50% will be refractory to conventional chemotherapy. It is now known that the majority of PLGG have activation of the ...
The impact of Housing First on criminal justice outcomes among homeless people with mental illness : a systematic review.
Objective: Housing First is increasingly put forward as an important component of a pragmatic plan to end homelessness. The literature evaluating the impact of Housing First on criminal justice involvement has not yet ...
Aging and language : maintenance of morphological representations in older adults
(Frontiers media, 2019-05-15)
Studies employing primed lexical decision tasks have revealed morphological facilitation effects in children and young adults. It is unknown if this effect is preserved or diminished in older adults. In fact, only few ...
A longitudinal investigation of sleep and daytime wakefulness in children and youth with concussion
A high proportion of adults who sustain a concussion identify changes in their sleep during the acute stage, typically reporting an increased need for sleep or nonrestful sleep. Our understanding of sleep following ...
Evidence of white matter changes on diffusion tensor imaging in frontotemporal dementia
(American Medical Association, 2007)
BACKGROUND: Two major clinical variants of frontotemporal dementia (FTD) have been described: frontal variant (fvFTD) and temporal variant (tvFTD). OBJECTIVE: To analyze white matter (WM) and gray matter (GM) tissue ...