Browsing Faculté des arts et des sciences – Département de psychologie - Travaux et publications by Author "Bocti, Christian"

Now showing items 1-4 of 4

  • Amyloid burden and white matter hyperintensities mediate age-related cognitive differences 

    Sévigny Dupont, Pénélope; Bocti, Christian; Joannette, Maude; Lavallée, Marie Maxime; Nikelski, Jim; Vallet, Guillaume; Chertkow, Howard; Joubert, Sven (Elsevier, 2019-08)
    This study examined the additive versus synergistic contribution of beta-amyloid (Aβ) and white matter hyperintensities (WMHs) across 7 cognitive domains in 104 cognitively normal older adults. It also measured the extent to which age-related differences ...

  • Education as a moderator of the relationship between episodic memory and amyloid load in normal aging 

    Joannette, Maude; Bocti, Christian; Sévigny Dupont, Pénélope; Lavallée, Marie Maxime; Nikelski, Jim; Vallet, Guillaume; Chertkow, Howard; Joubert, Sven (Oxford University Press, 2019-10-23)
    The current study explored whether education, a proxy of cognitive reserve, modifies the association between episodic memory (EM) performance and βeta-amyloid load (Aβ), a biomarker of Alzheimer’s disease, in a cohort of cognitively normal older ...

  • Subcortical amyloid load is associated with shape and volume in cognitively normal individuals 

    Subcortical Aβ associates to morphometry
    Rahayel, Shady; Bocti, Christian; Sévigny Dupont, Pénélope; Joannette, Maude; Lavallée, Marie Maxime; Nikelski, Jim; Chertkow, Howard; Joubert, Sven (Wiley, 2019-05-21)
    Amyloid-beta (Aβ) deposition is one of the main hallmarks of Alzheimer’s disease. The study assessed the associations between cortical and subcortical 11C-Pittsburgh Compound B retention, namely in the hippocampus, amygdala, putamen, caudate, pallidum, ...

  • Subcortical amyloid relates to cortical morphology in cognitively normal individuals 

    Rahayel, Shady; Bocti, Christian; Sévigny Dupont, Pénélope; Joannette, Maude; Lavallée, Marie Maxime; Nikelski, Jim; Chertkow, Howard; Joubert, Sven (Springer, 2019-07-25)
    Purpose Amyloid (Aβ) brain deposition can occur in cognitively normal individuals and is associated with cortical volume abnormalities. Aβ-related volume changes are inconsistent across studies. Since volume is composed of surface area and thickness, ...