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  • Nanonization of megestrol acetate by laser fragmentation in aqueous milieu 

    Sylvestre, Jean-Philippe; Tang, Marie-Christine; Furtos, Alexandra; Leclair, Grégoire; Meunier, Michel; Leroux, Jean-Christophe (2011-02-10)
    Nanonization is a simple and effective method to improve dissolution rate and oral bioavailability of drugs with poor water solubility. There is growing interest to downscale the nanocrystal production to enable early preclinical evaluation of new ...