Show item record

dc.contributor.authorLanglois, Roxane
dc.contributor.authorBenoit, Sophie
dc.contributor.authorRouleau, Isabelle
dc.contributor.authorVallet, Guillaume
dc.contributor.authorJoubert, Sven
dc.contributor.authorBarbeau, Emmanuel J.
dc.subjectEpisodic memoryfr
dc.subjectAlzheimer's diseasefr
dc.subjectAmnestic mild cognitive impairmentfr
dc.subjectEncoding deficitfr
dc.subjectRapid forgettingfr
dc.subjectMemory strengthfr
dc.titleAlzheimer’s disease and memory strength : gradual decline of memory traces as a function of their strengthfr
dc.contributor.affiliationUniversité de Montréal. Faculté des arts et des sciences. Département de psychologiefr
UdeM.statutProfesseur(e) / Professorfr
dcterms.abstractObjective : Episodic memory impairment is at the core of amnestic mild cognitive impair- ment (aMCI) and Alzheimer ’ s disease (AD). The origin of memory deficits may result either from an encoding deficit or from an accelerated decline of the memory trace. The present study explores these two hypotheses. Method : We used the delayed-matching-to sample 48 items (DMS-48) memory test in a group of controls, aMCI patients, and AD patients ( n = 16 in each group). The DMS-48 offers an incidental learning phase followed by three forced-choice recognition tests at three-minute, one-hour, and one-week delays. Moreover, the forced-choice test distinguishes three kinds of couple items: abstract (meaningless), paired (two similar exemplars), and unique (two different objects) items. Results : As predicted by the accelerated forgetting hypothesis, patients showed a decrease in recognition performance over time. Controls also exhibited a similar decline in performance. As predicted by the encoding deficit hypothesis, abstract items were the most poorly recognized in AD, at both the three-minute and the one-week delays. In AD, recognition of the paired items also dropped after the one-hour delay, followed by unique items after a one-week delay. Patients with aMCI exhibited a performance that was similar to controls, except for abstract items, which dropped at the one-week delay. Conclusions : These results are discussed in light of a third hypothesis, the memory strength hypothesis, in order to better account for the progressive decline in memory performance as a function of the item type in
UdeM.VersionRioxxVersion acceptée / Accepted Manuscript
oaire.citationTitleJournal of clinical and experimental neuropsychology

Files in this item


This item appears in the following Collection(s)

Show item record

DSpace software [version 5.8 XMLUI], copyright © 2002-2015  DuraSpace