Browsing École de santé publique – Travaux et publications by Author "Karp, Igor"

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  • The consumption of coffee and black tea and the risk of lung cancer 

    Pasquet, Romain; Karp, Igor; Siemiatycki, Jack; Koushik, Anita (2016-11-01)
    Purpose Coffee and black tea are among the most consumed beverages worldwide. While their potential role in lung cancer occurrence has been investigated in several studies, results have been inconclusive. We investigated the associations between ...

  • Genetic variants and early cigarette smoking and nicotine dependence phenotypes in adolescents 

    O’Loughlin, Jennifer; Sylvestre, Marie-Pierre; Labbe, Aurélie; Low, Nancy C.; Roy-Gagnon, Marie-Hélène; Dugas, Erika N.; Karp, Igor; Engert, James C. (Public Library of Science, 2014-12-29)
    Background: While the heritability of cigarette smoking and nicotine dependence (ND) is well-documented, the contribution of specific genetic variants to specific phenotypes has not been closely examined. The objectives of this study were to test ...

  • Missing single nucleotide polymorphisms in Genetic Risk Scores : a simulation study 

    Chagnon, Miguel; O’Loughlin, Jennifer; Engert, James C.; Karp, Igor; Sylvestre, Marie-Pierre (Public Library of Science, 2018-07-19)
    Using a genetic risk score (GRS) to predict a phenotype in a target sample can be complicated by missing data on the single nucleotide polymorphisms (SNPs) that comprise the GRS. This is usually addressed by imputation, omission of the SNPs or by ...