Adiposity and cardiac autonomic function in children with a family history of obesity
dc.contributor.author | Saade, Marie-Béatrice | |
dc.contributor.author | Holden, Samuel | |
dc.contributor.author | Lisa, Kakinami | |
dc.contributor.author | McGrath, Jennifer J. | |
dc.contributor.author | Mathieu, Marie-Ève | |
dc.contributor.author | Poirier, Paul | |
dc.contributor.author | Barnett, Tracie A. | |
dc.contributor.author | Beaucage, Pierre | |
dc.contributor.author | Henderson, Mélanie | |
dc.date.accessioned | 2024-09-30T15:48:18Z | |
dc.date.available | MONTHS_WITHHELD:12 | fr |
dc.date.available | 2024-09-30T15:48:18Z | |
dc.date.issued | 2024-09-21 | |
dc.identifier.uri | http://hdl.handle.net/1866/33817 | |
dc.publisher | Springer | fr |
dc.subject | Heart rate variability | fr |
dc.subject | Obesity | fr |
dc.subject | Pediatrics | fr |
dc.subject | Central adiposity | fr |
dc.title | Adiposity and cardiac autonomic function in children with a family history of obesity | fr |
dc.type | Article | fr |
dc.contributor.affiliation | Université de Montréal. Faculté de médecine. Département de pédiatrie | fr |
dc.contributor.affiliation | Université de Montréal. Faculté de médecine. École de kinésiologie et des sciences de l'activité physique | fr |
dc.contributor.affiliation | Université de Montréal. École de santé publique. Département de médecine sociale et préventive | fr |
dc.identifier.doi | 10.1007/s10286-024-01063-y | |
dcterms.abstract | Purpose Data on associations between adiposity and heart rate variability (HRV) in pre-pubertal children are limited. We examined the associations between adiposity indices and HRV, independent of lifestyle behaviors, comparing multiple indicators of adiposity, and explored differences between boys and girls. Methods Data stem from 469 participants of the QUALITY cohort (630 children aged 8-10 yrs with a parental history of obesity). Adiposity indices included waist-to-height ratio, body mass index (BMI) percentiles and categories (overweight, obesity), dual-energy x-ray absorptiometry (DEXA) defined fat mass percentage and android/gynoid ratio. HRV indices in the frequency and the spectral domain were derived from a daytime 3-hr Holter recording. Multivariable linear regression models were adjusted for age, sex, Tanner stage, physical activity, screen time, and fitness. Interactions between sex and adiposity were tested. Results Greater adiposity was associated with decreased parasympathetic modulation and increased sympathetic dominance. Waist-to-height ratio was associated with lower parasympathetic activity: RMSSD (B=-23.32 [-42.42, -4.22]), pNN50 (B=-16.93 [-28.58, -5.27]), LF/HF ratio (B=1.83 [0.97, 2.70]). Patterns of association were similar for android/gynoid ratio. Overweight was not associated with altered HRV. Obesity was negatively associated with RMSSD and pNN50 and positively with LF/HF ratio. Greater fat mass percentage was associated with lower RMSSD, pNN50 and HF, and increased LF/HF ratio. There were no differences between boys and girls. Conclusion Specific markers of adiposity relate to altered HRV in childhood, with waist-to-height ratio being potentially a more relevant marker of HRV than BMI and more pragmatic than percent body fat. NCT03356262, November 11, 2017. | fr |
dcterms.isPartOf | urn:ISSN:0959-9851 | fr |
dcterms.isPartOf | urn:ISSN:1619-1560 | fr |
dcterms.language | eng | fr |
UdeM.ReferenceFournieParDeposant | DOI: 10.1007/s10286-024-01063-y | fr |
UdeM.VersionRioxx | Version acceptée / Accepted Manuscript | fr |
oaire.citationTitle | Clinical autonomic research | fr |
Files in this item
This item appears in the following Collection(s)
This document disseminated on Papyrus is the exclusive property of the copyright holders and is protected by the Copyright Act (R.S.C. 1985, c. C-42). It may be used for fair dealing and non-commercial purposes, for private study or research, criticism and review as provided by law. For any other use, written authorization from the copyright holders is required.