The dementia-associated APOE ε4 allele is not associated with REM sleep behavior disorder
dc.contributor.author | Gan-Or, Ziv | |
dc.contributor.author | Montplaisir, Jacques-Yves | |
dc.contributor.author | Ross, Jay P. | |
dc.contributor.author | Poirier, Judes | |
dc.contributor.author | Warby, Simon | |
dc.contributor.author | Arnulf, Isabelle | |
dc.contributor.author | Strong, Stephanie | |
dc.contributor.author | Dauvilliers, Yves | |
dc.contributor.author | Leblond, Claire S. | |
dc.contributor.author | Hu, Michele T. M. | |
dc.contributor.author | Högl, Birgit | |
dc.contributor.author | Stefani, Ambra | |
dc.contributor.author | Monaca, Christelle | |
dc.contributor.author | Cochen De Cock, Valérie | |
dc.contributor.author | Boivin, Michel | |
dc.contributor.author | Ferini-Strambi, Luigi | |
dc.contributor.author | Plazzi, Giuseppe | |
dc.contributor.author | Antelmi, Elena | |
dc.contributor.author | Young, Peter | |
dc.contributor.author | Heidbreder, Anna | |
dc.contributor.author | Barber, Thomas R | |
dc.contributor.author | Evetts, Samuel G. | |
dc.contributor.author | Rolinski, Michal | |
dc.contributor.author | Dion, Patrick A. | |
dc.contributor.author | Desautels, Alex | |
dc.contributor.author | Gagnon, Jean-François | |
dc.contributor.author | Dupré, Nicolas | |
dc.contributor.author | Postuma, Ronald B. | |
dc.contributor.author | Rouleau, Guy | |
dc.date.accessioned | 2020-05-06T16:49:23Z | |
dc.date.available | NO_RESTRICTION | fr |
dc.date.available | 2020-05-06T16:49:23Z | |
dc.date.issued | 2016-10-13 | |
dc.identifier.uri | http://hdl.handle.net/1866/23341 | |
dc.publisher | Elsevier | fr |
dc.subject | APOE | fr |
dc.subject | REM sleep behavior disorder | fr |
dc.subject | Genetics | fr |
dc.subject | Parkinson's disease | fr |
dc.subject | Dementia with Lewy bodies | fr |
dc.title | The dementia-associated APOE ε4 allele is not associated with REM sleep behavior disorder | fr |
dc.type | Article | fr |
dc.contributor.affiliation | Université de Montréal. Faculté de médecine. Département de psychiatrie et d'addictologie | fr |
dc.identifier.doi | 10.1016/j.neurobiolaging.2016.10.002 | |
dcterms.abstract | The present study aimed to examine whether the APOE ε4 allele, associated with dementia with Lewy bodies (DLB), and possibly with dementia in Parkinson's disease (PD), is also associated with idiopathic rapid eye movement sleep behavior disorder (RBD). Two single nucleotide polymorphisms, rs429358 and rs7412, were genotyped in RBD patients (n = 480) and in controls (n = 823). APOE ε4 allele frequency was 0.14 among RBD patients and 0.13 among controls (OR = 1.11, 95% CI: 0.88–1.40, p = 0.41). APOE ε4 allele frequencies were similar in those who converted to DLB (0.14) and those who converted to Parkinson's disease (0.12) or multiple system atrophy (0.14, p = 1.0). The APOE ε4 allele is neither a risk factor for RBD nor it is associated with conversion from RBD to DLB or other synucleinopathies. | fr |
dcterms.isPartOf | urn:ISSN:0197-4580 | fr |
dcterms.isPartOf | urn:ISSN:1558-1497 | fr |
dcterms.language | eng | fr |
UdeM.ReferenceFournieParDeposant | Gan-Or, Z., Montplaisir, J. Y., Ross, J. P., Poirier, J., Warby, S. C., Arnulf, I., ... & Högl, B. (2017). The dementia-associated APOE ε4 allele is not associated with rapid eye movement sleep behavior disorder. Neurobiology of aging, 49, 218-e13. | fr |
UdeM.VersionRioxx | Version acceptée / Accepted Manuscript | fr |
oaire.citationTitle | Neurobiology of aging | |
oaire.citationVolume | 49 | |
oaire.citationStartPage | 218.e13 | |
oaire.citationEndPage | 218.e15 |
Fichier·s constituant ce document
Ce document figure dans la ou les collections suivantes
Ce document diffusé sur Papyrus est la propriété exclusive des titulaires des droits d'auteur et est protégé par la Loi sur le droit d'auteur (L.R.C. (1985), ch. C-42). Il peut être utilisé dans le cadre d'une utilisation équitable et non commerciale, à des fins d'étude privée ou de recherche, de critique ou de compte-rendu comme le prévoit la Loi. Pour toute autre utilisation, une autorisation écrite des titulaires des droits d'auteur sera nécessaire.