Faculté de pharmacie – Travaux et publications: Soumissions récentes
Voici les éléments 41-50 de 95
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A tutorial on dealing with time‐varying eligibility for treatment: Comparing the risk of major bleeding with direct‐acting oral anticoagulants vs warfarin
(Wiley, 2020-08-18)In this tutorial, we focus on the problem of how to define and estimate treatment effects when some patients develop a contraindication and are thus ineligible to receive a treatment of interest during follow-up. We first describe the concept of ... -
Impact of discretization of the timeline for longitudinal causal inference methods
(Wiley, 2020-09-01)In longitudinal settings, causal inference methods usually rely on a discretization of the patient timeline that may not reflect the underlying data generation process. This paper investigates the estimation of causal parameters under discretized ... -
Chitosan hydrogel micro-bio-devices with complex capillary patterns via reactive-diffusive self-assembly
(Elsevier, 2019-08-29)We present chitosan hydrogel microfluidic devices with self-assembled complex microcapillary patterns, conveniently formed by a diffusion-reaction process. These patterns in chitosan hydrogels are formed by a single-step procedure involving diffusion ... -
Synergy between zwitterionic polymers and hyaluronic acid enhances antifouling performance
(American Chemical Society, 2019-09-03)Challenges associated with nonspecific adsorption of proteins on sensor surfaces have steered the development of novel antifouling materials and strategies. Inspired by human synovial fluid composition and structure, we designed synergistic antifouling ... -
Interfacial forces across ionic liquid solutions : effect of ion concentration and water domains
(American Chemical Society, 2019-07-23)Using the surface force apparatus (SFA), the interaction forces between mica surfaces across ionic liquid (IL) solutions are studied. The IL solution, 1-hexyl-3-methylimidazolium bis(trifluoromethylsulfonyl)imide in propylene carbonate solvent, is used ... -
Electrostatic screening length in “soft” electrolyte solutions
(American Chemical Society, 2019-07-30)Using the Surface Forces Apparatus on solutions of polymeric ions, the effect of specific ion–ion correlations is evaluated on the characteristic decay length, λ, of screened electrostatic interactions between charged surfaces. Electrolyte solutions ... -
A multi-modal miniature surface forces apparatus (µSFA) for interfacial science measurements
(American Chemical Society, 2019-07-30)Advances in the research of intermolecular and surface interactions result from the development of new and improved measurement techniques and combinations of existing techniques. Here, we present a new miniature version of the Surface Force Apparatus ... -
Causal inference with multiple concurrent medications: a comparison of methods and an application in multidrug-resistant tuberculosis
(SAGE, 2018-10-31)This paper investigates different approaches for causal estimation under multiple concurrent medications. Our parameter of interest is the marginal mean counterfactual outcome under different combinations of medications. We explore parametric and ... -
Hotspot or blind spot? Historical perspectives on surveillance and response to epidemics in the Central African Republic
(Springer, 2020-02-12)Objectives The Central African Republic (CAR), a site of recurrent disease emergence, developed a noteworthy epidemiological surveillance system from the colonial period, but its health measures have remained among the world’s lowest. To understand ... -
Understanding and diagnosing the potential for bias when using machine learning methods with doubly robust causal estimators
(SAGE, 2018-05-02)Data-adaptive methods have been proposed to estimate nuisance parameters when using doubly robust semiparametric methods for estimating marginal causal effects. However, in the presence of near practical positivity violations, these methods can produce ...