Faculté de pharmacie – Travaux et publications: Soumissions récentes
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Monoclonal antibodies and immunotherapy : theory and applications
(2024)This document is an update of a previous one published on the Papyrus site of the University of Montreal in 2023. It takes into account new therapeutic targets as well as monoclonal antibodies approved last year by the FDA. This update consists of ... -
Anticorps monoclonaux et immunothérapie : théorie et applications
(2024)Ce document est une mise à jour d’un précédent publié sur le site Papyrus de l’Université de Montréal en 2023. Il tient compte des cibles thérapeutiques nouvelles ainsi que des anticorps monoclonaux agréés l’an dernier par la FDA. Cette mise à jour ... -
Deep tissue penetration of bottle-brush polymers via cell capture evasion and fast diffusion
(American Chemical Society, 2022-12-14)Drug nanocarriers (NCs) capable of crossing the vascular endothelium and deeply penetrating into dense tissues of the CNS could potentially transform the management of neurological diseases. In the present study, we investigated the interaction of ... -
Monoclonal antibodies and immunotherapy : theory and applications
(2023-06-27)The primary goal of this course is to provide the theoretical background necessary to better understand the mechanism of immunotherapy and in particular the mode of action of monoclonal antibodies currently available in immunotherapy. -
Anticorps monoclonaux et immunothérapie : théorie et applications
(2023-06-27)Le but premier de ce cours est de fournir les bases théoriques nécessaires pour mieux comprendre les mécanismes de l’immunothérapie et en particulier le mode d’action des anticorps monoclonaux actuellement disponibles en immunothérapie. -
(In)stability of ligands at the surface of inorganic nanoparticles : a forgotten question in nanomedicine?
(Elsevier, 2022-06-14)Multiple inorganic nanoparticles (NPs) are currently being developed for nanomedicine. Various core materials and shapes are explored, but they all display a common hybrid structure, with organic ligands on their surface. These ligands play a key role ... -
Short-sequence superadhesive peptides with topologically en-hanced cation-π interactions
(American Chemical Society, 2021-06-03)In this study, using the surface force apparatus, we report engineered peptides with short sequences of phenylalanine (F) and lysine (K) amino acids capable of forming the most efficient cation−π interactions reported for underwater adhesive systems ... -
A quantitative UHPLC-MS/MS method for the growth hormone-releasing peptide-6 determination in complex biological matrices and transdermal formulations
A quantitative UPLC-MS/MS method for the growth hormone-releasing peptide-6 determination in complex biological matrices and transdermal formulations
(Elsevier, 2021-05-26)Growth hormone-releasing peptide-6 (GHRP-6) is part of a group of small synthetic peptides with potent GH-releasing activity that have gained attention in the last two decades by virtue of their cyto- and cardioprotective effects. Despite numerous ... -
Recent developments in natural and synthetic polymeric drug delivery systems used for the treatment of osteoarthritis
(Elsevier, 2021-01-12)Osteoarthritis (OA), is a common musculoskeletal disorder that will progressively increase in older populations and is expected to be the most dominant cause of disability in the world population by 2030. The progression of OA is controlled by a ... -
Phytoglycogen nanoparticles : nature-derived superlubricants
(American Chemical Society, 2021-05-07)Phytoglycogen nanoparticles (PhG NPs), a single-molecule highly branched polysaccharide, exhibit excellent water retention, due to the abundance of close-packed hydroxyl groups forming hydrogen bonds with water. Here we report lubrication properties ...